Is PEMF an Effective Treatment of Bone Fractures and Bone Healing?
Translational Insights into Extremely Low Frequency Pulsed Electromagnetic Fields (ELF-PEMFs) for Bone Regeneration after Trauma and Orthopedic Surgery
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947624/
The review clearly shows that ELF-PEMFs represent a valuable adjunct to conventional therapy for bone and osteochondral defects.
Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945722/
The review showed the possible efficacy of PEMF as a non-invasive, low-cost, and safe method to improve bone healing. However, further investigations are needed to establish a gold standard treatment protocol and to optimize treatment in clinical practice.
Pulsed Electromagnetic Field Stimulation of Bone Healing and Joint Preservation: Cellular Mechanisms of Skeletal Response
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434032/
Clinical efficacy of PEMF exposure in accelerating healing of fresh fractures and osteotomies has been demonstrated. The study also highlighted the lack of negative adverse effects and the local field of biological activity as notable advantages of PEMF.
Pulsed Electromagnetic Fields in Bone Healing: Molecular Pathways and Clinical Applications
https://www.mdpi.com/1422-0067/22/14/7403
The study discussed the clinical application of PEMFs and the molecular pathways involved in bone healing. It emphasized the approval of PEMFs by the FDA as a safe and effective treatment for nonunions of bone since 1979.
Pulsed Electromagnetic Field Stimulation of Bone Healing… : JAAOS Global Research & Reviews
https://journals.lww.com/jaaosglobal/fulltext/2020/05000/
The study demonstrated the clinical efficacy of PEMF exposure in accelerating healing of fresh fractures and osteotomies. It also highlighted the lack of negative adverse effects and the local field of biological activity as notable advantages of PEMF.
These studies collectively suggest that PEMF therapy holds promise for improving bone healing, accelerating fracture repair, and promoting joint preservation. However, further research is needed to establish standardized treatment protocols and optimize its clinical application.
Pulsed Electromagnetic Field Affects the Development of Postmenopausal Osteoporotic Women with Vertebral Fractures
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302368/
A non-operative salvage of surgically-resistant pseudarthroses and non-unions by pulsing electromagnetic fields. A preliminary report, 1977
Bassett CAL, Pilla AA, Pawluk RJ. Orthopaedic Research Laboratories, College of Physicians and Surgeons, and Department of Chemical and Applied Engineering, Columbia University, NY, NY – The Biochemistry Section ESB, Inc. Yardley, PA, USA
Repair of Non-Unions by Pulsing Electromagnetic Fields, 1978
Bassett CA, Mitchell SN, Norton L, Pilla
A Treatment of non-union of bone fractures by pulsing electro-magnetic fields, 1982
Hutchings J., UK.
Pulsed magnetic field therapy for tibial non-union. Interim results of a double-blind trial. 1984
Barker AT, Dixon RA, Sharrard WJ, Sutcliffe ML. Lancet. 1984 PMID: 6143970
11 The development and application of pulsed electromagnetic fields (PEMFs) for ununited fractures and arthrodeses. 1985
Bassett CA. Clin Plast Surg. 1985 Apr;12(2):259-77. PMID: 3886262 Review.
A randomized double-blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions, 1989
Mooney V. University of California Irvine, Division of Orthopaedic Surgery, Irvine, CA, USA
Role of pulsed electromagnetic fields in recalcitrant non-unions.
Delima DF, Tanna DD. J Postgrad Med. 1989 Jan;35(1):43-8. PMID: 2585337
Healing of nonunion of a fractured lateral condyle of the humerus by pulsing electromagnetic induction, 1991
Das Sarkar S, Bassett CA, Department of Orthopaedic Surgery, Sandwell District General Hospital, Lyndon, West Midlands, UK.
Effects of static magnetic and Pulsed Electro-Magnetic Fields on bone healing, 1997
Darendeliler MA, Darendeliler A, Sinclair, PM. Discipline of Orthodontics, Faculty of Dentistry, University of Sydney, Australia.
Pulsed Electro-Magnetic Fields for the treatment of bone fractures, 1999
Satter Syed A, Islam MS, Rabbani KS, Talukder MS., Industrial Physics Division, BCSIR Laboratories, Dhaka.
Exposure to pulsed magnetic fields enhances motor recovery in cats after spinal cord injury, 2003
Crowe MJ, Sun ZP, Battocletti JH, Macias MY, Pintar FA, Maiman DJ., Neuroscience Research Laboratories, The Clement J. Zablocki VA Medical Center, Milwaukee, WI, USA.
Pseudarthrosis after lumbar spine fusion: nonoperative salvage with Pulsed Electro-Magnetic Fields, 2004
Simmons JW Jr, Mooney V, Thacker I. UTMB, Galveston, Texas, USA.
Reversal of delayed union of anterior cervical fusion treated with pulsed electromagnetic field stimulation: case report, 2004
Mackenzie, Donald, and Francis D Veninga
Pulsed electromagnetic field (PEMF) treatment for fracture healing, 2009
Boopalan, PRJVC et al.
Is There Still A Role For Pulsed Electromagnetic Field in the Treatment of Delayed Unions and Nonunions, 2008
REC Rose, Division of Orthopaedics, Department of Surgery, Radiology, Anaesthesia and Intensive Care, The University of the West Indies, BA Bryan-Frankson, Physical Therapy Solutions, El Shaddai Medical Centre, Jamaica
Effects of pulsed electromagnetic stimulation on patients undergoing hip revision prostheses: A randomized prospective double-blind study, 2009
Dante Dallari et al., VII Division of Orthopaedic and Traumatology, Rizzoli Orthopaedic Institute, Bologna, Italy
Effect of pulsed electromagnetic fields on human osteoblast cultures
S Barnaba, R Papalia, L Ruzzini… – … Research …, 2013 – Wiley Online Library Bioelectromagnetics 2002; 23: 398– 405
Pulsed Electromagnetic Fields (PEMF) Inhibit Matrix Metalloproteinase-13 Expression in Human Annulus Fibrosus Cells
X Tang, R Willardson, D Coughlin… – The Spine …, 2014 – thespinejournalonline.com
Inductively Coupled Electrical Stimulation-Part 2: Optimization of parameters for orthopedic injuries and pain
R Dennis – The Journal of Science and Medicine, 2019 – josam.org